UQ adds to the bank with breakthrough drug therapy deal

A deal has been stitched together by the University of Queensland and its commercialisation arm UniquestĀ  to develop a unique drug delivery method to mental health patients.

Jul 29, 2021, updated May 22, 2025
Dr Harendra Parekh demonstrating the sol-gel technology
Dr Harendra Parekh demonstrating the sol-gel technology

The deal, with InnarisBio, a division of German bio-pharmaceutical company Atai Life Sciences, is for nasal spray technology that enables the delivery of psychedelic and non-psychedelic drugs to treat mental health disorders.

UQ researcher Dr Harendra Parekh and his team developed the solution-to-gel intranasal drug delivery technology. It uses a liquid solution containing the therapeutic compound that converts to a gel upon contact with the inside membrane of the nose.

Atai plans to explore the use of the sol-gel technology for a variety of compounds in its development pipeline.

UniQuest negotiated the licence agreement which includes a patent application and its chief executive Dean Moss said the technology would potentially play a role in solving one of the world’s most complex health problems.

ā€œIt could help tackle the burden of mental illness and is another example of the power of UQ research to create meaningful change,ā€ Moss said.

UniQuest will receive equity in InnarisBio, along with the potential to receive future development and commercial milestone payments and a royalty on sales.

Uniquest does not reveal its finances other than to say that it has contributed $700 million to the university in the past decade through commercialising bio techs

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Atai chief executive and co-founder Florian Brand said UQ’s team had worked hard to develop a technology that may mitigate many of the drawbacks typically associated with traditional drug delivery to the central nervous system, which had such a large unmet need.

ā€œThis novel technology has the potential to be superior to other intranasal drug delivery methods available by improving absolute uptake and duration of uptake through muco-adhesion in the nose, reducing dose administered and dosing frequency,ā€ he said.

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Head of UQ School of Pharmacy Professor Sarah Roberts-Thomson said it was an exciting development for the sol-gel technology.

ā€œWe are delighted to partner with InnarisBio – supported by global biopharmaceutical company atai Life Sciences – to address an area of such great unmet need,ā€ she said.

InnarisBio will collaborate with UniQuest, UQ’s Parekh and his research team to formulate and develop bespoke sol-gel formulations for several psychedelic and non-psychedelic compounds nominated by InnarisBio.

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